Abstract
Objectives: To develop and assess a photoprotective and antioxidant formulation based on the association between titanium dioxide (TiO2) and buriti vegetable oil (Mauritia flexuosa L).
Methods: The emulsion was developed by the phase inversion method and the physicochemical and organoleptic parameters were evaluated according to ANVISA guidelines. The sun protection factor (SPF), UVA/UVB ratio and critical wavelength of the formulation were evaluated in silico. In the photostability test, buriti oil samples were exposed to solar radiation between 10 am and 3 pm. The areas over the curves (AUC) of the absorption spectra of the control sample and the irradiated samples were calculated.
Results: At the concentration of 10% titanium dioxide (TiO2), the theoretical values of SPF = 18.6, UVA/UVB ratio of 0.31 and critical wavelength of 379 nm were obtained. The final formulation presented a light beige color, characteristic odor of buriti oil, homogeneous aspect and an average pH of 5.9. In the preliminary stability study, the formulation was stable, with no changes in color, odor, appearance and pH during the entire test period. Buriti oil was considered photounstable in all ranges of the absorption spectrum, which may be related to the presence of β-carotene and tocopherols, which are photosensitive compounds.
Conclusion: The formulation was stable in terms of organoleptic and physicochemical properties, however, buriti oil was considered photounstable. Future research may confirm photoinstability or promote actions to ensure the photostability of the oil in the formulation.
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